(R)-1-(7-硝基苯并[C][1,2,5]噁二唑-4-基)吡咯烷-3-胺
(R)-(-)-NBD-APY
CAS: 143112-51-0
Molecular Formula: C10H11N5O3
(R)-1-(7-硝基苯并[C][1,2,5]噁二唑-4-基)吡咯烷-3-胺 - Names and Identifiers
| Name | (R)-(-)-NBD-APY |
| Synonyms | (R)-(-)-NBD-APY HPLClabelingreagentfore.e.determ (R)-(-)-4-(3-AMINOPYRROLIDINO)-7-NITROBENZOFURAZAN (R)-(-)-4-NITRO-7-(3-AMINOPYRROLIDIN-1-YL)BENZOFURAZAN (R)-(-)-1-(7-NITRO-4-BENZOFURAZANYL)-3-PYRROLIDINAMINE (3R)-1-(4-nitro-2,1,3-benzoxadiazol-7-yl)pyrrolidin-3-amine (R)-(-)-4-NITRO-7-(3-AMINOPYRROLIDIN-1-YL)-2,1,3-BENZOXADIAZOLE |
| CAS | 143112-51-0 |
| InChI | InChI=1/C10H11N5O3/c11-6-3-4-14(5-6)7-1-2-8(15(16)17)10-9(7)12-18-13-10/h1-2,6H,3-5,11H2/t6-/m1/s1 |
(R)-1-(7-硝基苯并[C][1,2,5]噁二唑-4-基)吡咯烷-3-胺 - Physico-chemical Properties
| Molecular Formula | C10H11N5O3 |
| Molar Mass | 249.23 |
| Density | 1.494±0.06 g/cm3(Predicted) |
| Melting Point | ~190°C (dec.) |
| Boling Point | 469.7±55.0 °C(Predicted) |
| Flash Point | 237.9°C |
| Vapor Presure | 5.37E-09mmHg at 25°C |
| Appearance | powder to crystal |
| Color | Orange to Brown |
| pKa | 8.38±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.678 |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
(R)-1-(7-硝基苯并[C][1,2,5]噁二唑-4-基)吡咯烷-3-胺 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 9 |
(R)-1-(7-硝基苯并[C][1,2,5]噁二唑-4-基)吡咯烷-3-胺 - Introduction
R-(-)-4-nitro-7-(3-aminopyrroline) 2,1, 3-benzoxazole, often abbreviated as R-Nitro-APB, is an organic compound.
Nature:
R-Nitro-APB is a solid crystal with a white or white-like color. Its chemical formula is C12H9N5O2 and its relative molecular mass is 271.24g/mol. The melting point of this compound is about 174-176°C. It dissolves in acetic anhydride and is poorly soluble in water.
Use:
R-Nitro-APB is a research compound that is often used to synthesize new drugs. It has some properties that affect the human central nervous system, so it is widely used in drug research.
Preparation Method:
The preparation method of R-Nitro-APB is complicated and generally requires a multi-step reaction. These include the reaction of p-2-phenylpropionic acid, followed by the introduction of the nitro group by the reaction of nitrosamide compounds, and finally the introduction of the 3-aminopyrroline group by an electrophilic aromatic substitution reaction.
Safety Information:
R-Nitro-APB is a very strong research compound with potential risks to humans. Since its mechanism of action has not yet been fully grasped, it requires careful operation when using it. Follow the laboratory safety guidelines and wear protective gloves, glasses and laboratory coats when performing experiments. At the same time, it is necessary to comply with the laboratory waste treatment specifications when conducting experiments to avoid environmental pollution.
Nature:
R-Nitro-APB is a solid crystal with a white or white-like color. Its chemical formula is C12H9N5O2 and its relative molecular mass is 271.24g/mol. The melting point of this compound is about 174-176°C. It dissolves in acetic anhydride and is poorly soluble in water.
Use:
R-Nitro-APB is a research compound that is often used to synthesize new drugs. It has some properties that affect the human central nervous system, so it is widely used in drug research.
Preparation Method:
The preparation method of R-Nitro-APB is complicated and generally requires a multi-step reaction. These include the reaction of p-2-phenylpropionic acid, followed by the introduction of the nitro group by the reaction of nitrosamide compounds, and finally the introduction of the 3-aminopyrroline group by an electrophilic aromatic substitution reaction.
Safety Information:
R-Nitro-APB is a very strong research compound with potential risks to humans. Since its mechanism of action has not yet been fully grasped, it requires careful operation when using it. Follow the laboratory safety guidelines and wear protective gloves, glasses and laboratory coats when performing experiments. At the same time, it is necessary to comply with the laboratory waste treatment specifications when conducting experiments to avoid environmental pollution.
Last Update：2024-04-09 21:11:58
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